Decoquinate , a new type highly-efficienct quinolones anti-coccidiosis


Decoquinate is a new type highly-efficienct quinolones anti-coccidiosis for livestock and poultry, commonly known as quinoxetine, decanoquinolate, paclitaxel, to quinolate, benzoquinone. The active compound is white or slightly yellow crystalline powder, rarely soluble in chloroform or ether, insoluble in water or ethanol. It has a unique anti-coccidial activity stronger than Maduramicin, nicarbazine + Ethanamidobenzylate, methyl salicin. Studies have shown that decanoquinolines are effective in combating the resistance from coccidium and are clinically used to control the most harmful poultry coccidiosis caused by E.tenella, E.maxima, E.acerVulina, E.necatrix, E.brunetti, E.mivati). it can also effect in the precaution of neosporosis in livestocks of cattle and sheep. It can improve the weight growth rate and milk yield of young goat.
Decoquinate plays a role in the asexual reproduction of coccidia, and after entering the sporozoite cell, it prevents its development by interfering with DNA synthesis. It begins to function in the early stages of life history of coccidia, effectively prevents the coccidia caused by intestinal damage. Addition of decoquinate in the fodder does not affect the digestion of the fodder and the absorption of nutrients.
This product has no incompatibility except that it can not be used in the feed containing bentonite.
Quinoline anticoccidial drugs are easy to be resisted. It is recommended continuous use of up to no more than 4 weeks be applied only in the peak period of coccidia,.
Since the 1970s, decanoquinolines have been widely used in the control of coccidiosis in poultry in many countries, but have not been used in China.
In 2006, quinoline was first introduced  into China market, which had aroused wide attention. Its first use in China had presented no drug resistance, its use as ideal alternative, killing effect on coccidia, promoting effect on growth, improvement effect on the color, excellent anticoccidial effect and growth performance in the early life; it starts to play a role in the early stages of life history of coccidia with the longest effect duration and a wide anticoccidial spectrum. It has extermination effect on the most harmful 6 avian coccidia with an excellent stability. It can keep stable quality for 4 years at proper temperature and humidity.

 

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