Fosfomvcin Sodium is used to treat infections caused by Staphylococcus aureus, Escherichia coli, Proteus and Shigella


Fosfomvcin Sodium can be combined with a bacterial cell wall synthase, which prevents bacteria from using the relevant substances to synthesize the first step of the cell wall reaction, thereby playing a bactericidal role. For Staphylococcus, Streptococcus pneumoniae, Escherichia coli, Neisseria gonorrhoeae, Proteus mirabilis, Typhoid fever, Serratia, most Pseudomonas aeruginosa, Streptococcus pyogenes, Streptococcus faecalis, some indole positive Proteus and certain Klebsiella and Enterobacter bacteria have antibacterial effects.

1. Broad antibacterial spectrum, high bioavailability, fast absorption, strong antibacterial ability, not affected by diet. It can kill Gram-positive bacteria and negative bacteria, especially Pseudomonas aeruginosa, Proteus, Salmonella, Staphylococcus and Escherichia coli that are resistant to various drugs can show excellent antibacterial activity. Used in animals, there is no drug resistance and cross-resistance, good clinical treatment effect 2. Rapid sterilization: This product is a rapid bactericide, and its effect is obvious after 1-2 hours. About 25% of Escherichia coli was killed 1 hour after exposure to Fosfomvcin (12.5 μg / ml), and all died within 4-6 hours. Pseudomonas aeruginosa and Staphylococcus aureus were also killed in 4 and 8 hours, respectively.

3. Low toxic and side effects, little irritation to the body, no acute toxicity and adverse reactions, will not increase the burden on the kidneys.

4. Low residue: The elimination time to reach the residue standard in muscles and organs is 48-72 hours.

It is mainly used for the treatment of acute and chronic intestinal diseases caused by Staphylococcus, Streptococcus, Escherichia coli, Salmonella and other Gram-negative bacteria in chickens, ducks and pigs. For drinking water for livestock and poultry: add 5-10 grams of this product per 100kg of water, twice a day for 3 days. For livestock and poultry mix: add 10-15 grams of this product to 100kg of feed, twice a day for 3 days.

 

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