Fucoxanthin—–The panacea for weight loss

Fucoxanthin is a kind of xanthin, a substance that makes brown algae appear brown. It can be said to be a unique pigment of brown algae, and it is sometimes scattered in diatoms and other algae. Sometimes confused with phycofuscin, but phycofuscin is considered to be a water-soluble pigment unique to brown algae, and it seems to be a hypothetical substance. It seems to refer to a kind of phenol contained in brown algae after plant death. A yellowish-brown substance formed after the substance is oxidized, so they are completely different in nature.The content of raspberry ketones in raspberries is not high. On the contrary, some tropical fruits are very rich in raspberry ketones. Among them, tava fruit is the most abundant, and its raspberry ketone content is 300 times that of raspberries. Therefore it is called “the king of fiber fruits”.

Absorption and metabolism

Fucoxanthin and taxaxanthin A are the main primary metabolites of fucoxanthin. The ingested fucoxanthin is hydrolyzed into fucoxanthin under the action of digestive enzymes in the gastrointestinal tract, and then enters the systemic circulation through the lymph. Part of the fucoxanthin is degraded in the liver to taxaxanthin A, fucoxanthin and tax yellow Element A is then further metabolized by enzymatic reactions such as isomerization, dehydrogenation, deacetylation, oxidation and demethylation.

Safety

Fucoxanthin has no effect on liver, kidney, spleen and gonadal tissue, but it can cause hypercholesterolemia. Fucoxanthin has no teratogenicity in vitro, and fucoxanthin has no teratogenicity in vivo at doses of 500, 1000, and 2000 mg/kg.

Stability

High-purity fucoxanthin is unstable to heat and easily oxidized. However, the fucoxanthin extract obtained from algae is stable due to the co-existence of antioxidant substances.

Fucoxanthin pigment is sensitive to light, and its stability is greatly improved when stored in the dark. At the same time, other antioxidants can protect the fucoxanthin pigment from degradation. In addition, fucoxanthin pigments are more stable than neutral and acidic under alkaline pH conditions, and have the greatest stability at pH 9 and the most unstable under acidic conditions.