Furazolidone is mainly used as a fungicide for the treatment of various intestinal infections

Furazolidone is what we usually call dysentolin, a kind of nitrofuran antibacterial, which has a certain antibacterial effect on Gram-positive and negative bacteria, and is also active against Trichomonas and Giardia at a certain concentration. Its mechanism of action is to interfere with bacterial oxidoreductase and thereby block the normal metabolism of bacteria. Mainly used for the treatment of various intestinal infections, bacterial dysentery, diarrhea, enteritis, E. coli septicemia, typhoid fever, cholera, infectious rhinitis, blackhead disease, trichomoniasis, leukocyte disease of Kaposi, and can also be used with And other drugs in combination to treat gastritis caused by Helicobacter pylori.

As an animal medicine and beverage additive, it has a special antibacterial effect against Salmonella, such as Shigella dysenteriae and Escherichia coli, and also has a certain effect on protozoa (coccidiosis, etc.), and it is not easy to appear drug resistance. A small amount of furazolidone is used as a fungicide in other applications (such as water-soluble coatings and pulp).

Furazolidone is very toxic to fish, turtles, etc., and can be used for both prevention and early disease treatment in freshwater fish farming. When the water temperature is below 20 ° C, dip for 20 to 30 minutes; when the water temperature is above 20 ° C, dip for 10 to 15 minutes. When the water temperature is around 20 ℃, furazolidone concentration of 0.025ppm can inhibit various pathogenic bacteria. Goldfish and tropical fish raised in pools and water tanks can tolerate 1.5ppm concentration and will not die. Therefore, in case of serious illness, 0.4-1.0ppm concentration can be used. After the medicine is sprayed in the whole pond, domestic fish should be fed with high-quality commercial feed. Such as animal food, strengthen the nutrition of sick fish and enhance the disease resistance of sick fish. To prevent white-head and white-mouth disease, gill disease, printing disease, vertical scale disease, and red skin disease of domestic fish, soak them once before stocking. To prevent white-head and white-mouth disease, gill rot disease, vertical scale disease, and decayed tail disease of ornamental fish, they are immersed in small water bodies once a day, and then immersed once every other day. For the treatment of white-headed white-mouth disease, gill disease, vertical scale disease, decayed tail disease of ornamental fish, etc., immerse once a day, then immerse once every other day, and can be immersed continuously for 3 to 5 times until Symptoms disappear, and the fish returns to health.