Sodium hyaluronate, also known as sodium hyaluronate, is a physiologically active substance widely present in animals and humans. It is distributed in human skin, joint synovial fluid, umbilical cord, aqueous humor, and eye vitreous. A polymer polysaccharide biomaterial formed by repeated alternating acids. This product has a high degree of viscoelasticity, plasticity, and good biocompatibility, and plays a significant role in preventing adhesions and repairing soft tissues. Can be used for adjuvant treatment of deformed knee joint disease and periarthritis of the shoulder, clinically used for a variety of skin injuries, promote wound healing, for abrasions and lacerations, leg ulcers, diabetic ulcers, compression ulcers, and Debridement and venous stasis ulcers are effective. Sodium hyaluronate is the main component of joint synovial fluid and is one of the components of cartilage matrix. It functions as a lubricating agent in the joint cavity, covering and protecting articular cartilage, improving joint contracture, inhibiting the surface of cartilage degeneration, improving pathological joint fluid, and increasing slippery function.
Hyaluronidase can be used as a proteolytic enzyme. Generally used to accelerate the absorption of muscle and subcutaneous injections, reduce pain at the injection site, promote the infiltration of local anesthetics, and help to promote the dissipation of local edema or hematoma after surgery and trauma. Can also be used for intestinal adhesions. But salicylic acid can inhibit the action of hyaluronidase.