Indoxacarb has contact killing and stomach toxic effects. It is a broad-spectrum and highly effective insecticide, effective against larvae of all instars

Indoxacarb is the first commercially available oxadiazine insecticide. Laboratory bioassays and field efficacy tests show that indoxacarb is effective against almost all important agricultural scales such as cotton bollworm, tobacco budworm, diamondback moth, cabbage caterpillar, beet armyworm, pink armyworm, blue armyworm, codling moth, etc. Pteran pests have excellent insecticidal activity, and have certain effects on some homopteran and coleoptera pests such as small green leafhopper, potato leafhopper, green peach aphid, potato beetle, etc. Using high performance liquid chromatography and mass spectrometry techniques to study the metabolism of Hc-labeled indoxacarb in lepidopteran insects, it was found that indoxacarb can be rapidly converted into N-demethoxycarbonyl metabolites (DCJW) by lepidopteran insects This conversion mainly occurs in the midgut and fat body, and can be inhibited by esterase inhibitors paraoxon and defoliphos (DEF). It is speculated that the related catalytic enzyme may be an esterase. Further studies have found that the generation ten transformation of indoxacarb is different between different insects. Compared with non-lepidopteran insects, most of the lepidopteran larvae can quickly transform 90% after administration. Indoxacarb is converted to DCJW, and compared with indoxacarb, DCJW is more effective in blocking the combined action potentials of the abdominal motor neurons of tobacco hornworm larvae. It is speculated that indoxacarb‘s activation metabolism rate and its insecticidal activity in different insects Related to selectivity, this is why indoxacarb is low in toxicity to mammals and other non-target organisms.

Indoxacarb exerts insecticidal activity (larvicide and oviparison) through contact and stomach poisoning. The insects stop feeding within 3 to 4 hours, become imbalanced, paralyzed, and eventually die. Although indoxacarb has no systemic effect, it can enter the mesophyll through osmosis.

Indoxacarb is not easy to decompose even when exposed to strong ultraviolet light and is still effective at high temperatures. It is resistant to rain washing and can be strongly absorbed on the leaf surface. Indoxacarb has a broad insecticidal spectrum, and it protects against lepidopteran pests, Curculionidae, leafhoppers, bugs, apple fruit flies and corn root pests on vegetables, fruit trees, corn, rice, soybeans, cotton and grapes. The effect is particularly good.

Indoxacarb gel and bait are used to prevent and control sanitary pests, especially for the control of cockroaches, fire ants and ants. Its sprays and baits can also be used to control lawn worms, weevils and mole crickets.

Unlike traditional carbamate insecticides, indoxacarb is not a cholinesterase inhibitor, and no other insecticide has the same mechanism of action. Therefore, indoxacarb, pyrethroids and organophosphates have not been found Class and carbamate insecticides are cross-resistant. After more than 10 years of commercial use, indoxacarb has not been found to be harmful to any labeled crops.

In the United States, indoxacarb is positioned as the only lepidopteran insecticide that can control the American Lygus.

Since indoxacarb is insoluble in water, highly effective, low-toxic, and non-chronic, it has been developed as an ideal red fire ant bait in the United States and is widely used in the control of red fire ants.