In recent years, ruminant nutritionists have conducted a lot of research on choline nutrition in dairy cows and achieved certain results. However, reports on the effects of adding RPC in diets on milk performance and blood biochemical indicators of high-yielding dairy cows vary.
For high-yield dairy cows in the perinatal period, the physiological characteristics of decreased feed intake and increased energy demand often lead to negative energy balance. Body fat mobilization produces a large amount of free fatty acids, which leads to increased fat deposits in the liver, resulting in varying degrees of liver fat infiltration , Affecting the production performance and reproductive performance of dairy cows.
Choline is an important component of very low-density lipoprotein (VLDL) and the methyl donor of carnitine. Choline supplementation can increase the liver’s ability to oxidize and export fat, and reduce liver fat deposition. Due to the degradation of rumen microorganisms, the biological potency of directly adding choline is very low, so it is necessary to supplement rumen protective choline (RPC).
Most research results show that supplementation of RPC can improve the efficiency of milk cow fat mobilization to a certain extent, improve the body’s energy balance, and reduce the occurrence of ketosis and fatty liver. This may be due to the fact that choline generates betaine through the choline oxidation pathway, and then indirectly participates in the synthesis of S-adenosylmethionine through the methionine remethylation pathway, and then through the use of S-adenosylmethionine as the active methyl The methyl metabolism of the base donor promotes the synthesis of carnitine, enhances the oxidation of fatty acids in the tissue, improves the degradation of fatty acids by the tissue, and finally achieves the effect of reducing animal fat deposition.
In addition, the concentration of BHBA in plasma is closely related to the performance of dairy cows. Supplementing RPC has a certain promotion effect on milk production. One of the possible reasons is that choline promotes the decrease of BHBA in plasma.
In short, supplementing RPC to high-yielding dairy cows during the perinatal period can increase milk production, improve milk quality, especially promote liver fat output and oxidative utilization to a certain extent, improve fat metabolism in dairy cows, alleviate negative energy balance, and reduce liver fat deposition danger.