Inhibition of silymarin on lipoxygenase and peroxidase. It is clinically used for the treatment of liver poisoning, liver dysfunction, anti-radiation and hypolipidemic effect.
A large number of studies have shown that silymarin and silybin compounds have a wide range of pharmacological activities. The main activities are summarized as follows:
Clear active oxygen
Directly remove active oxygen, resist lipid peroxidation, and maintain cell membrane fluidity;
Hepatoprotective effect
Silymarin has a protective effect on liver damage caused by carbon tetrachloride, galactosamine, alcohols and other hepatoxins;
Antitumor effect
Various reactive oxygen species can oxidize guanine to form 8-orthinoguanine, causing DNA damage and then tumors. The use of antioxidants, especially free radical scavengers, can prevent this process from occurring;
Anti-cardiovascular disease effect
Ksoottva et al. studied the oxidation of high-cholesterol and low-density lipoproteins by silymarin extract in mice. Mice were fed with polyunsaturated fatty acids and a small amount of saturated fatty acid food containing silymarin extract. In mice with a small amount of saturated fatty acids, the cholesterol content in the serum of the former was significantly reduced, VLDL hair was reduced, and HDL-C increased, indicating that silymarin has improved the ability to resist LDL;
Protective effects of cerebral ischemia
Feng Quan et al. Explored the protective mechanism of silymarin on cerebral ischemic injury in rats by using a four-vascular blockage model of global cerebral ischemia. It was shown that silymarin significantly reduced the infarct size while significantly reducing the content of NO and NOS in the brain tissue of ischemic rats. Therefore, it is concluded that silymarin can improve the antioxidant capacity of the body and has a significant protective effect on cerebral ischemic injury.
After years of research by Puyer group technical team, we found that Silymarin’s main function in aquatic products is to protect the liver and eliminate reactive oxygen species. The use of this pure natural organic ingredient will improve the quality of aquatic products and increase economic benefits. At present, this product has been used in Chile, Saudi Arabia and Egypt, and has received unanimous praise from customers.