Vinpocetine is used for enhancing memory and preventing Alzheimer’s disease

Vinpocetine is a man-made chemical resembling a substance found in the periwinkle plant Vinca minor. People use it as medicine.

Vinpocetine is a cerebrovascular dilatation drug that has a long-term effect on vinblastine and selectively increases cerebral blood flow; it can improve and improve the supply of cerebral oxygen, promote metabolism, enhance the deformability of red blood cells, reduce blood viscosity, and inhibit platelets Gather and improve brain tissue metabolism. Mainly used for the treatment of sequelae of cerebral infarction, sequelae of cerebral hemorrhage, cerebral arteriosclerosis, etc. It is also used to treat retinal arteriosclerosis and vasospasm, deafness and dizziness in the elderly.

Vinpocetine is a semi-synthetic vinblastine derivative. The effect is similar to vinblastine, and it has a high selective expansion effect on cerebral blood vessels. The pharmacological effects are as follows:

1.Inhibit the activity of calcium-dependent phosphodiesterase, increase the cAMP content of relaxing vascular smooth muscle, thereby relaxing vascular smooth muscle, and increase cerebral blood flow.

2.Enhance the deformability of red blood cells, reduce blood viscosity, inhibit platelet aggregation, thereby improving blood fluidity and microcirculation.

3.Promote the uptake of glucose by brain tissue and promote the metabolic transformation of monoamine in the brain.

4.During cerebral ischemia, it can inhibit the increase of lactic acid in the brain, increase the content of ATP, inhibit the production of lipid peroxides in the brain, delay the occurrence of cerebral ischemic spasm, so it can improve brain metabolism and protect brain function.

Vinpocetine is also used for preventing and reducing the chance of disability and death from ischemic stroke. This is the type of stroke that occurs when a blood clot stops blood flow in the brain, causing brain cells (neurons) to die because they are not receiving oxygen. People try vinpocetine for preventing and treating stroke right after it happens because they think vinpocetine might help keep blood from clotting and might also protect neurons against the harmful effects of oxygen deprivation. Other uses for vinpocetine include treating symptoms of menopause, chronic fatigue syndrome (CFS), and seizure disorders; and preventing motion sickness.