FOXO4-DRI CAS:2460055-10-9

Product Detail Name: FOXO4-DRI CAS:2460055-10-9 Feature: FOXO4-DRI is a cell-permeable peptide comprising part of the p53-interaction domain of FOXO4.  It can compete with endogenous FOXO4 for p53, thereby disrupting the FOXO4-p53 interaction. Disrupting the p53-FOXO4 interaction causes p53 to be excluded from the nucleus and directed to mitochondria for induction of apoptosis in senescent cells, ultimately eliminating senescent fibroblasts through triggering apoptosis[1-2]. FOXO4-DRI to be selective for ionizing radiation-induced senescent IMR90 cells and safe to normal cells. Composition: Appearance: White powder Assay: 99% Packing: 25kg/drum or as discussed Shelf Life: 2 years Storage: Store in cool and dry area Certification:ISO GMP KOSHER HALAL