Berberis HLC——A BOUVARBIN

Berberis HLC is a yellow needle-like crystal, bitter quaternary ammonium alkaloid. It was extracted from Coptis chinensis (Ranunculaceae), Berberis vulgaris and other plants in the early stage. Now it is possible to produce hydrochloric acid or berberine sulfate in large quantities by synthetic methods.

Clinically, because of its broad-spectrum antibacterial effect, Berberine HLC is often used in the treatment of dysentery and gastroenteritis, so it is called “BOUVARBIN”. Berberine HLC generally stays in the intestine after oral administration, so it has fewer side effects. The latest clinical studies have found that Berberine HLC can reduce hyperlipidemia (high cholesterol and triglycerides) by about 30%, so it is widely regarded.

What is the effect of Berberine HLC?

Broad-spectrum antibacterial: including inhibition of such as Shigella, Mycobacterium tuberculosis, Streptococcus hemolyticus, Staphylococcus aureus, Neisseria gonorrhoeae, pneumococcus, typhoid bacillus and diphtheria bacillus. Among them, it has the strongest effect on Shigella, so it is often used for gastroenteritis, diarrhea and other gastrointestinal diseases, and has little side effects. However, Shigella, Streptococcus hemolyticus, Staphylococcus aureus, etc. are easily resistant to this product.

Anti-fungal and anti-viral: It also has a certain inhibitory effect on influenza virus, amoeba protozoa, Leptospira, and certain skin fungi.

Lowering blood lipids: Clinical studies have shown that oral Berberine HLC at a dose of 1000 mg/day for 3 consecutive months can reduce total cholesterol, low-density lipoprotein (“bad” cholesterol) and triglycerides by 25-35%.

Anti-heart failure and anti-arrhythmia: The latest research has found that Berberine HLC has anti-inflammatory and antihypertensive effects, and can improve heart failure and arrhythmia patients.

Diabetes and obesity: The latest research shows that oral berberine can activate AMPK (adenosine monophosphate activated protein kinase) to promote glucose metabolism, fat metabolism, etc., enhance glucose tolerance and inhibit fat synthesis.

Berberine HLC has been used clinically as an over-the-counter drug to treat diarrhea, but modern pharmacological studies have confirmed that Berberine HLC has significant anti-heart failure, anti-arrhythmic, lower cholesterol, anti-vascular smooth muscle proliferation, improvement of insulin resistance, anti-platelet, and anti-inflammatory Therefore, it may have a wide range of important application prospects in cardiovascular system and nervous system diseases, and it will be paid more and more attention.