Chromium pyridine formate (CrPic) is a complementary or alternative drug for type 2 diabetes

Chromium pyridine formate, also known as chromium pyridine carboxylate, chromium methyl pyridine, purple red crystalline powder, good fluidity, stable at room temperature, slightly soluble in water, insoluble in ethanol, in which chromium is trivalent chromium.

Chromium pyridine formate (CrPic) is a complementary or alternative drug for type 2 diabetes. Experimental evidence suggests that CrPic plays a role in glucose uptake through p38 MAPK activation. Chromium is thought to increase insulin function, leading to increased insulin sensitivity in type 2 diabetes.

Chromium is an important component of glucose tolerance factor (GTF). It can increase the activity of insulin, participate in protein synthesis, nucleic acid and fat metabolism, and reduce the body fat content. Chromium can also strengthen the immune system and improve the body’s resistance to adverse conditions and stress.

Main functions

(1) as a functional factor of medicine and health care products: hypoglycemia and lipid suppression, weight loss supplement, strong muscle and healthy body, and immune enhancement.

(2) as feed additive:

1. Increase the yield and survival rate of livestock, poultry, eggs, milk and young;

2. Promote the rapid growth of livestock and poultry by lowering blood glucose and inhibiting fat, and improve the rate of return of feed;

3. Adjust the internal secretion to enhance the reproduction performance of livestock and poultry;

4. Improve carcass quality and lean meat ratio;

5. Reduce the stress of livestock and poultry, and enhance the anti-stress ability of livestock and poultry;

6. Enhance the immune function of livestock and poultry, and reduce the risk of livestock and poultry breeding.

Recent studies have found that chromium picolinate increases the amount of an active AMP protein kinase (AMPK) associated with metabolic pathways in skeletal muscle cells, thereby improving energy balance and insulin function. The research was led by Dr. William Cefalu, a lecturer at the nutrition and chronic disease research unit at Pennington biomedical center, whose findings were detailed this week by Dr. Zhong Wang, a lecturer at the 41st annual meeting of the European association for the study of diabetes, held in Athens, Greece.

Active AMP protein kinase (AMPK) is a control and many other metabolic pathways including blood glucose uptake is an important enzyme, and is associated with insulin resistance and type Ⅱ diabetes.” “Prior studies have not addressed the mechanism of chromium action and its possible effects on AMPK.” “While there have been numerous studies on the effects of prescription drugs, food, and exercise on AMPK, this is the first time that this enzyme has been shown to be affected by nutritional therapy,” Cefalu said. These results are preliminary and need further study. Provided at the national institutes of health research funding, we will further study the pathogenesis of human Ⅱ diabetes.”

The application of chromium pyridine formate in diabetes mellitus is an indisputable fact, and the effect is obvious. But some patients and even doctors do not know about chromium pyridine formate, say what have, some even said that clenbuterol, feed additives, western medicine, and so on, in fact chromium pyridine formate is a mineral, a kind of human body essential trace element. It is reported that the United States department of agriculture nutrition center and other authoritative institutions confirmed again in the latest research, trivalent inorganic chromium to enhance the activity of insulin is very small, when the conversion into organic chromium will have a significant role in strengthening the activity of insulin. As an important component of glucose tolerance factor, chromium pyridine formate is an indispensable trace element in diabetic patients. Studies have shown that chromium pyridine formate is highly stable and, as a fat-soluble non-electrolyte, can act directly on tissue cells through the cell membrane smoothly, enhance insulin activity, improve human glucose metabolism, and play an important role in the treatment of diabetes. It is suitable for diabetic people and people with abnormal glucose tolerance, high-risk groups of diabetes and healthy people.