Hexapeptide-2——A new kind of whitening polypeptide

As the saying goes, one white hides one hundred ugliness. In the Weibai era, do you want to be a beautiful scenery among the crowd?

 

The main culprit for skin injury is ultraviolet light, which stimulates the black pigment in the skin and induces skin disease. Even in cloudy and cold winters, the “ultraviolet rays” are still strong. Ultraviolet rays can also cause skin darkening, aging, and skin wrinkles. There is also humid air, sunlight coming in through car windows, even indoor lamp tubes, and radiation from computers and mobile phones.

 

Moreover, the synthesis process of melanin is quite complicated, which is a multi-step enzymatic biochemical reaction. First, after the melanocytes in the skin take up tyrosine, it is oxidized to (3,4-dihydroxyphenylalanine) under the action of tyrosinase containing copper ions, and then oxidized to dopaquinone. Dopaquinone quickly becomes dopachrome through intramolecular cyclization, and dopachrome undergoes intramolecular rearrangement to form 5,6-dihydroxyindole and 5,6-dihydroxyindole-2-carboxylic acid. The intermediates finally form 5,6-indolequinone and 5,6-dihydroxyindolic acid, which together form melanin. Tyrosinase is a key enzyme for melanin synthesis, and its quantity and activity are related to the rate of melanin synthesis.

 

This is why, if a certain part is often exposed to sunlight in summer, the skin tone layering will be obvious.

 

So how can it become a landscape among the crowd in vain?

 

The first thing is to reduce UV exposure and do a good job of sun protection.

 

Secondly, starting from the root cause, inhibit the production of melanin.

 

Hexapeptide-2 is an antagonist of α-MSH, which reduces the level of cyclic adenosine monophosphate, inhibits tyrosinase activity, reduces unnecessary pigment production and calmness, controls skin tone and prevents brown spots. By competitively blocking the entrances of receptors and various factor signals on melanocytes, the activity of melanocytes is weakened and the amount of melanin production is reduced.