New feed additive for preventing and treating intestinal infection and improving livestock and poultry diarrhea — Bacitracin Methylene Disalicylate

Bacitracin Methylene Disalicylate has a strong effect on Gram-positive bacteria. The main mechanism is to inhibit the synthesis of bacterial cell walls.

Effects on gut microbes

1. Resistant to Gram-positive bacteria, especially sensitive to Clostridia. The main component of the cell wall of Gram-positive bacteria is peptidoglycan, accounting for 65-95% of the total cell wall. Methylene salicylic acid peptides prevent the transport of peptidoglycan precursors, thereby inhibiting the synthesis of peptidoglycans, and therefore have a strong effect on Gram-positive bacteria.

2. Effect on Gram-negative bacteria

(1) The special effect of methylene salicylic acid bacitracin on E. coli, by affecting the integrity of the cell wall of E. coli, enhancing the sensitivity of anti-G-drugs, thereby reducing the resistance of chlortetracycline and ampicillin in the intestine The number of Escherichia coli, and reduce the spread of resistant plasmids in E. coli (2) reduce the spread of Salmonella; (3) methylene salicylic acid peptides against some Gram-negative bacteria such as meningococcus and tether The genus Fungi, Amoeba and Bovine Actinomycetes have an inhibitory effect.

3. The role of beneficial bacteria in the intestine

The US FDA experiments show that methylene salicylic acid bacitracin has no inhibitory effect on intestinal beneficial bacteria such as Lactobacillus, Bifidobacterium, and Bacillus.

Application effect

1. Promote animal growth and improve feed conversion rate

Methylene salicylic acid bacitracin can promote intestinal villi growth, increase villi surface area, thus improve feed digestibility, promote nutrient absorption, and ultimately promote animal growth and improve feed remuneration.

2. Maintain intestinal health and reduce the occurrence of loose stools, feed stools, water stools and blood stools

Excessive proliferation of harmful microorganisms will lead to indigestion of livestock and poultry, and disorder of water absorption and reabsorption, causing diarrhea (diarrhea, feed stool, water stool, blood stool, etc.) Methylene salicylic acid bacitracin can prevent intestinal infection, maintain intestinal health, and significantly improve the diarrhea of ​​livestock and poultry.