Sulfamethoxazole Sodium for the treatment of infectious diseases of livestock digestive tract caused by sensitive bacteria infection

Sulfamethoxazole Sodium is a sulfonamide antibacterial and anti-inflammatory drug used to prevent Salmonella and E. coli infections in livestock and poultry. Such as: chicken white dysentery, chicken typhoid fever, avian E. coli, piglet yellow, white dysentery, and paratyphoid of young animals have a good effect on urinary tract and respiratory tract infections caused by Pasteurella bovis, avian cholera and sensitive bacteria. Prevention and treatment of aquatic animal aeromonosis, pseudomonas disease, Edwardsiosis, vibriosis etc. Application of this product is prone to hematuria, and sodium bicarbonate needs to be added in large doses.

Sulfamethoxazole Sodium requires the same amount of sodium bicarbonate to alkalize urine and promote its excretion to reduce its damage when taking Sulfamethoxazole Sodium. The experiment designed Sulfamethoxazole Sodium group, Sulfamethoxazole Sodium + sodium bicarbonate group, sodium bicarbonate group. Gram-negative bacteria sensitive to sinomenine: dysentery bacillus, typhoid bacillus, typhoid bacillus type B, Escherichia coli, and Gram-positive (bacillus) pneumoniae, streptococcus (D) group were selected as experiments bacteria. Experiments have shown that although sodium bicarbonate itself has no bacteriostatic effect, it has a synergistic effect on the bacteriostatic effect of Sulfamethoxazole Sodium. This experiment does not suggest that sodium bicarbonate has an antagonistic effect on the bacteriostatic effect of Sulfamethoxazole Sodium. It is inferred that when taking Sulfamethoxazole Sodium, patients taking the same amount of sodium bicarbonate can not only prevent the precipitation of Sulfamethoxazole Sodium in the renal tubule, but also have Enhance the effect of medicine.

Applications:

1. Used for enterotoxin syndrome of livestock, poultry and aquatic animals

2. Treatment of diarrhea in young animals

The preparation of this group is used to treat infectious diseases of the digestive tract of young animals caused by sensitive bacterial infections. The clinical manifestations are: diarrhea, dyspnea and other symptoms. Individual severe cases also show dehydration and neurological symptoms. Such as: calves pulling cement-like stench loose stools; lambs bowing their heads back without eating or pulling stench loose stools with yellow, green, yellow-white or gray-white, later blood, and some abdominal distension without diarrhea, the sick lamb finally dehydrated and appeared nervous Symptoms and death, anatomical evidence of undigested milk clumps or food masses in the stomach; yellow and white dysentery and cement-like loose stools in piglets; white dysentery, umbilitis, yolk inflammation and dyspnea in chicks.

In the application of the above new formulation, as a preference, the young animals include calves, lambs, piglets and chicks. The method has the characteristics of broad antibacterial spectrum and strong effect, and has the advantages of short treatment course, fast effect, low price, good efficiency in treating diarrhea of young animals, short treatment time and high cure rate, and has a synergistic effect between the ingredients.