Amprolium Hydrochloride is used in chickens, rabbits, calves and lambs, and is effective on tender and heap-shaped Eimeria and lamb and calf coccidia. It is suitable for use with other drugs to make water-soluble powders or premixes. It is the main anticoccidial drug for laying hens. The product has low toxicity, large safety range, little residue, and no need for drug withdrawal period. It is usually made with ethoxyamide benzyl methyl ester and sulfaquinoxaline to expand the anticoccidial spectrum and enhance the anticoccidial effect. Combining it with sulfaquinoxaline also has a good inhibitory effect on concurrent bacterial infections, and it is a widely used anticoccidial drug.
This product is effective for chicken tender and heap type Eimeria, lamb and calf coccidia. Aminoproline can inhibit the growth and reproduction of the first generation of schizonts. Taking Eimeria gallis as an example, the peak period of action is on the third day after infection. In addition, the gametocytes and sporophytes of the sexual cycle also have a certain degree of inhibition, which can be used to prevent and treat coccidiosis. Its mechanism of action is that the chemical structure of amphetamine is similar to that of thiamine. Therefore, it can replace thiamine in the metabolic process of the worm, causing coccidiosis to cause thiamine deficiency and interfere with its metabolism.
If thiamine is added to the feed, it can counteract the effect of amphetamine. The combination of amphetamine and sulfaquinoline (mixed feeding and drinking water administration) can expand the range of anticoccidial, and is safe and effective. Aminoproline has a good effect on cecal coccidiosis. Ethoxyamide benzyl ester and sulfaquinoline mainly act on intestinal coccidia. Their combined use (mixed feeding or drinking water administration) can expand the range of anticoccidial, and is safe and effective Used as a premix.